Overall narrative:
Based on advanced equipment manufacturing concepts, combined with the characteristics of mammalian cell culture processes, equipped with internationally renowned instrument valves and control systems. A&M Technology Co., Ltd has developed a glass bioreactor with independent proprietary technology. It is suitable for cell culture or bacterial fermentation from small to pilot stages of drugs such as monoclonal antibodies, vaccines or recombinant proteins.
Product description:
● Working volume: 2L/5L/10L optional;
● Number of tanks: 2-10 optional;
● Aspect-to-height ratio: 1:2-3; Liquid filling coefficient: 75%;
● Tank body: a combination of high temperature resistant, acid and alkali corrosion resistant borosilicate glass cylinder and 316L stainless steel;
● Stirring method: Shaft transmission mechanical stirring or magnetic stirring;
● Ventilation: Mass flow meter display, adjust gas flow according to process requirements;
● PH control: Intelligent PID control, which can be controlled in conjunction with CO2 or acid pump;
●DO control: optical dissolved oxygen electrode, intelligent PID control, which can be controlled in conjunction with ventilation, rotational speed, and feeding;
● Temperature control: intelligent PID control, electric heating, water cooling;
● Feeding: Complete feeding system (acid, alkali, defoaming, feeding), programmable feeding;
● Sterilization: Off-site sterilization.
Parameters:
Item | Specification |
Stirring speed | Using servo drive motor, wide range, low noise, range: 50-1000rpm, accuracy: ±1rpm |
PH control | Intelligent PID control, peristaltic pump automatically replenishes acid/alkali; mass flow meter automatically replenishes CO2, range: 2-12pH; Control accuracy: ±0.02pH |
DO control | Intelligent PID control, which can be related to the feeding speed; range: 0-150%, control accuracy: ±5% |
Temperature control | Intelligent PID control; electric heating, water cooling; Range: +5-60℃; Accuracy: ±0.2℃ |
Foam control | Electrode detection, peristaltic pump to replenish defoaming agent, automatic control |
Ventilation | Mass flow meter to accurately control flow according to process requirements |
Tank pressure alarm | Manual adjustment, pressure gauge display; range: 0-0.1Mpa |
Control system optional | Siemens S7-1200 series PLC control system and imported industrial computer |
Full Chinese menu and interface | USB flash drive can be used for data transmission, sampling and display of tank data, browsing and analysis of system data, and reading of settings |
Added optional functions | Feeding balance weighing, online detection of cell density, online detection of OD value, online detection of exhaust gas, etc |
Features:
● Simple and versatile: used for laboratory cell culture, off-site sterilization, easy operation, powerful functions, and can meet various culture purposes, such as batch culture, fed-batch culture, and perfusion culture;
● Flexible use: The color touch screen displays all measurement values and control parameters, which greatly facilitates user operation. Four peristaltic pumps are installed on the front of the operating table, which can replenish acid, alkali, defoaming agent and culture medium to the cell tank;
● Control system: Various parameters such as pH, DO, temperature and rotation speed can be monitored through the controller. All data records, operation records and alarm records can be transferred to the controller or computer for storage and export, and remote Web access is supported;
● Stirring system: It adopts overhead magnetic or mechanical coupling driving stirring method, which is tightly sealed to reduce the probability of contamination; it has a compact structure and a variety of replaceable blades to meet various cell culture needs.
Product details:
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