BP-S stainless steel bioreactor

Overall description:

It is suitable for suspension and adherent culture of eukaryotic and prokaryotic cells. It provides a full range of products from 2L small trials, pilot trials to large-scale production. It is suitable for the production of biological products such as monoclonal antibodies, vaccines, and recombinant proteins. Based on the advanced control system, the configuration complies with ISA-88 standards and provides a complete file system that meets GMP requirements.
Product description:
Based on advanced equipment manufacturing and automation architecture concepts, combined with the characteristics of mammalian cell culture processes, equipped with internationally renowned instrument valves and control systems, A&M Technology Co., Ltd has developed stainless steel bioreactors with independent core technology. It is suitable for pilot scale to commercial production of drugs such as antibody drugs, vaccines or recombinant proteins.

● Derived from international leading design and manufacturing concepts;
● Working capacity: 30L-5000L;
● Fully automatic CIP/SIP, feeding, inoculation, harvesting, etc.;
● A variety of stirring paddles fully meet the growth of different cells and viruses;
● Powerful control system, friendly HMI, convenient operation;
● The basic configuration is supplemented by a wealth of expandable options to meet various budget and process requirements;
● Provide a full set of equipment manufacturing documents and verification documents.

Parameters:

Stirring Speed: Speed: 10~800rpm infinitely variable; accuracy: ±1rpm
PH Control: Range: 2~12ph; Control accuracy: ±0.02pH, Resolution: 0.01pH
DO Control: Can be related to speed; range: 0~150%, control accuracy: ±5%; resolution: 0.1%,

Temperature Control: Range: cooling water temperature +5~55℃; Accuracy: ±0.2℃; Resolution: 0.1℃
Foam Control: Electrode detection, peristaltic pump automatically replenishes defoaming agent.
Ventilation Control: Automatic adjustment, flow meter display; range: 0.1-3vvm
Tank pressure Control: Automatic adjustment, pressure gauge display; range: 0~0.20MPa

Features:

● The perfect combination of bioprocess experts and equipment experts to create high-efficiency bioreactors.
● Rich configurations, enabling online sampling, CIP/SIP, online measurement of cell density, glucose and OPR.
● CFD optimizes the height, angle, size, etc. of the blades to provide better mixing effects and reduce shear force.
● Multiple air distribution methods: circular air distribution, ventilation cage air distribution, etc.
● Suitable for batch/fed-batch/perfusion culture. For perfusion culture, rotating filter or external circulation separation membrane can be selected.
● Highly stable and powerful control system, friendly and easy-to-operate HMI.

Product details: